Who says there are no second acts in American business? These four tech moguls have got it goin’ on — again.

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WHO: Mitch Kapor
OLD GIG: Founded Lotus
Development and created Lotus 1-2-3 spreadsheet application
NEW GIG: Runs Open Source Applications Foundation; at work on Chandler, a software app that could revolutionize desktop data management

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WHO: Elon Musk
OLD GIG: Founded PayPal, the online payment service he sold to eBay for $1.5 billion in 2002
NEW GIG: CEO of SpaceX, which builds lower-cost launch vehicles to ferry satellites into space

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WHO: Todd Wagner
OLD GIG: Cofounder of Broadcast.com (with Mark Cuban); sold to Yahoo! in ’99 for $5.7 billion
NEW GIG: Philanthropist who helps inner-city kids; heads 2929 Entertainment, a production company; and is an investor in Cuban’s HDNet TV network

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WHO: Marc Andreessen
OLD GIG: Cocreator of Netscape, the first popular web browser; boffo ’95 IPO made him rich; sold to AOL in 1999 for $4.2 billion
NEW GIG: Runs OpsWare (formerly LoudCloud), which makes IT automation software; EDS is a major customer