Rat Race follows the Survivor-like adventures that ensue when a Las Vegas casino owner sets up a gambling scheme where people bet on which of six candidates will find the $2 million he has hidden somewhere in the U.S. The hilarious tale includes a huge ensemble cast featuring Rowan Atkinson (Mr. Bean), Kathy Bates, Dean Cain, Whoopi Goldberg, John Cleese, and Cuba Gooding Jr., among many others.

The Farrelly Brothers’ newest creation, Osmosis Jones,, is an animated and live-action film that stars Chris Rock as a white blood cell trying to hunt down and destroy a new virus in Frank’s body (played by Bill Murray). This one is sure to be another side-splitter from the writers of Something About Mary, but be prepared for bodily function humor to descend to a whole new level.