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Kenneth Willardt/Corbis Outline

Hall Pass star Alyssa Milano is still a fan favorite three decades into her career.

Since becoming a child star in the 1980s, Alyssa Milano has taken on plenty of roles: Model. Producer. Singer. Author. Philanthropist. Entrepreneur. Ask which one she identifies with the most, though, and she’ll pick a role that’s a little more down-to-earth.

“I always joke that I’m the eternal cousin,” says the 38-year-old, who appears in the new Farrelly Brothers comedy, Hall Pass. That’s how she describes her accessibility to fans, the ones who grew up watching her on long-running series like Who’s The Boss? and Charmed. That friendliness explains in part why she’s still so popular, belonging to Twitter’s elite million-followers club. “People feel like they know me, and I’m approachable,” she says. “That’s a very winning combination to keeping your sanity in [Hollywood].”

But if Milano bears the qualities of a cousin, she’s certainly a hip one — and a busy one too. Last year alone, she starred in a Lifetime movie and a short-lived series called Romantically Challenged; did a guest spot on Castle; expanded her successful clothing line (see sidebar, below); and took on her first motion-picture production role for the independent My Girlfriend’s Boyfriend, in which she also starred. She’s also fiercely dedicated to charitable work, capping off 2010 the same way she did the year before — with an online birthday drive, in which she raised $1,000 for every year of her life to build wells in developing African regions.

“I think I’m an overachiever,” Milano laughs. “But I wouldn’t feel fulfilled as a human being if I didn’t contribute to humanity. My career has afforded me a voice strong enough to effect positive change.”

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In Touch
In 2005, lifelong Los Angeles Dodgers fan Alyssa Milano fumed when she walked into the Dodger Stadium memorabilia shop. “Nothing was made specifically for a woman’s body,” she says. Within months, she started a line called Touch by Alyssa Milano, which offers form-fitting women’s apparel for every major league team and many NCAA teams. In addition to an online store, there are two Touch boutiques (at Pittsburgh’s Consol Energy Center and New York’s Citi Field), with plans for more at stadiums nationwide. www.fandalia.com